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Allopurinol

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From £14.95

Includes FREE Private Prescription.

* This treatment requires an online consultation for review by our prescribing team. The decision to supply the specific treatment and quantity requested will be based on whether our medical team are satisfied that it will be safe, appropriate, and effective. Please note that you must be 18 years of age or older to request this treatment.

Place your order by 1pm to receive delivery as soon as the next day!

 

Prevents Gout attacks

Lowers the level of uric acid in the body

Xanthine Oxidase Inhibitor

 

What is Allopurinol and how does it work?

Allopurinol belongs to a class of medicines known as Xanthine Oxidase Inhibitors, which work by lowering the level of uric acid in the blood and urine. Allopurinol helps to prevent Gout attacks by limiting the formation of uric acid crystals that deposit and build up in joints and tendons, causing painful inflammatory reactions.

Allopurinol is a preventative medication and not a treatment for a flare of Gout, it does not have any effect during a Gout attack and it is not a painkiller. Allopurinol takes around 2-3 months to become fully effective and should be taken on a regular basis to keep the uric acid level normal in order to prevent Gout attacks.

Allopurinol may be advised if you:

  • Have had two or more attacks of Gout within a year
  • Have one or more tophi
  • Have any joint or kidney damage due to Gout
  • Have one or more kidney stones made from uric acid
  • Have had a Gout attack and are taking long-term medication that can cause Gout

Additional Information

How should I take Allopurinol?

Before taking Allopurinol, you should read the manufacturer’s printed Patient Information Leaflet (PIL) from inside the pack. It will give you more information about Allopurinol and provide you with a full list of the side effects which you may experience from taking it.

The initial dose for the prevention of Gout is 100mg daily, adjusted if necessary according to uric acid concentration. The usual maintenance dose is 100-300mg daily, however, this can increase up to 900mg in severe cases. Tablets should be taken after food and swallowed with a glass of water.

If you are an older person or if you have reduced liver or kidney function, you may be prescribed a lower dose or told to take it at longer intervals. If you have dialysis two or three times a week, your doctor may prescribe a dose of 300 or 400mg which is to be taken straight after your dialysis.

When you first take Allopurinol, it can sometimes cause a Gout attack. For this reason, it is not normally started during a flare. It is best to start it about 3-4 weeks after an attack has settled. Once the level of uric acid has been brought down, taking Allopurinol each day usually works well to prevent Gout attacks.

If a Gout attack occurs while you are taking Allopurinol, you can still take an anti-inflammatory painkiller to relieve the pain. However, this may indicate that you need an increased dose of Allopurinol.

 

Usual maintenance dose in mild conditions

100–200mg daily, dose to be taken preferably after food.

Usual maintenance dose in moderately severe conditions

300–600mg daily in divided doses (max. per dose 300mg), dose to be taken preferably after food

Usual maintenance dose in severe conditions

700–900mg daily in divided doses (max. per dose 300mg), dose to be taken preferably after food.

 

If you take more Allopurinol than you should, contact a doctor or go to hospital straight away. Take the medicine pack with you. Signs of an overdose may include nausea, vomiting, diarrhoea, and dizziness.

If you forget a dose, take it as soon as you remember it. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten dose.

Do not stop taking Allopurinol without talking to your doctor.

Along with their useful effects, most medicines can cause unwanted side effects although not everyone experiences them. The unwanted effects often improve as your body adjusts to the new medicine, but please speak with your doctor or pharmacist if they continue or become troublesome. You will find a full list of possible side effects in the Patient Information Leaflet (PIL) supplied with your medicine.

If you have a hypersensitivity (allergic) reaction, stop taking Allopurinol and seek medical help immediately. The signs may include:

  • Flaking skin, boils, or sore lips and mouth
  • Very rarely signs may include sudden wheeziness, fluttering or tightness in the chest, and collapse

 

Common side effects (may affect up to 1 in 10 people)

  • Skin rash
  • Increased level of Thyroid Stimulating Hormone (TSH) in the blood

Please tell the prescriber if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription. This is because Allopurinol can affect the way some medicines work, and some medicines can have an effect on Allopurinol. In the event of a medical emergency, you should tell your doctor, pharmacist, or nurse that you have taken Allopurinol and when you did. Do not take Allopurinol with other medicines unless your doctor tells you that you can.

Tell your doctor or pharmacist if you are taking any of the following medicines:

  • Aspirin
  • Theophylline, used for breathing problems
  • Medicines used for fits (epilepsy), Phenytoin
  • Vidarabine, used to treat herpes or chickenpox
  • Antibiotics (Ampicillin or Amoxicillin)
  • Didanosine, used to treat HIV infection
  • Medicines used for cancer
  • Medicines used to reduce your immune response (immunosuppressants)
  • Medicines used to treat diabetes
  • Medicines for heart problems or high blood pressure such as ACE inhibitors or water tablets (diuretics)
  • Medicines used to thin your blood (anticoagulants), such as Warfarin
  • Any other medicine to treat Gout

 

If Aluminium hydroxide is taken concomitantly, Allopurinol may have an attenuated effect. There should be an interval of at least 3 hours between taking both medicines.

With administration of Allopurinol and cytostatics (e.g. Cyclophosphamide, Doxorubicin, Bleomycin, Procarbazine), blood dyscrasias occur more frequently than when these active substances are administered alone. Blood count monitoring should therefore be performed at regular intervals.

Do not take Allopurinol:

  • If you are allergic (hypersensitive) to Allopurinol, or any of the ingredients listed in the Patient Information Leaflet supplied with your medication

 

Warnings & Precautions

Talk to your doctor or pharmacist before taking Allopurinol:

  • If you are of Han Chinese, African or Indian origin
  • If you have problems with your liver or kidneys. You may be prescribed a lower dose and monitored more closely
  • If you have heart problems or high blood pressure and you take diuretics and/or ACE inhibitors
  • If you are currently having an attack of Gout
  • If you have thyroid problems

 

Pregnancy, Breastfeeding, & Fertility

  • There is inadequate evidence of the safety of Allopurinol in pregnancy, although it has been in wide use for many years without apparent ill consequence. Use in pregnancy only when there is no safer alternative and when the disease itself carries risks for the mother or unborn child
  • Allopurinol during breastfeeding is not recommended

 

Driving and using machinery

You may feel drowsy, giddy, or have problems with your coordination. If this happens, do not drive or use any tools or machines.

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Step 3 - Express Delivery of Your Chosen Treatment

Once your order has been approved by our prescriber, your treatment is then dispensed, packaged, and posted by our regulated pharmacy partner. Your order will arrive as quickly as the next day depending on your selected delivery option.

You can be confident that your treatment will be 100% genuine, safe, and effective as we only use medications procured from licensed manufacturers and trusted UK wholesalers.

Rest assured that your treatment will be delivered in plain packaging for complete discretion.

Step 2 - Complete a Short Medical Questionnaire

A straightforward medical questionnaire acts as a replacement to the conventional face-to-face appointment. This type of consultation process is quick and should only take around five minutes to complete.

The questionnaire consists of simple questions regarding your general health and the specific condition selected. Questions are easy to understand and similar to those that you would be asked during a GP appointment.

The online assessment is completely private and confidential and is conducted with the same professionalism and safety standards as you would expect from a regular appointment but without the need for an awkward or embarrassing face-to-face consultation.

When the questionnaire has been completed, you can add your chosen treatment to your basket and complete our secure checkout process.

Our fully accredited and qualified UK prescriber then screens your completed medical questionnaire and assesses your suitability for treatment. If the prescriber has any additional questions or concerns, they will contact you directly for clarification.

Provided that the prescriber is satisfied that the treatment is appropriate, the order will be approved, and a free private prescription issued for dispensing. In the event that your order is refused, you will be informed of the reason and given referral advice.

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